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Vincristine br Contents lists avail iframe width height
2020-08-18
Contents lists available at ScienceDirect Chemical Engineering Journal journal homepage: www.elsevier.com/locate/cej Black phosphorus nanosheets-based stable drug delivery system via drug- T self-stabilization for combined photothermal and chemo cancer therapy Gan Liua,b, Hsiang-I Tsa
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23986-74-5 br Biotin vitamin H is an essential micronutrient
2020-08-18
Biotin (vitamin H) is an essential micronutrient, which is vital for normal cellular function (Livaniou et al., 2000). Owing to low mole-cular weight, relatively simple biochemical structure, and high tumor specificity, biotin has attracted great attention from pharmaceutical research. In order to
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br Molecular Therapy br applies
2020-08-18
Molecular Therapy applies to other solid tumors, which would make them very attractive anticancer agents. MATERIALS AND METHODS Cell Lines PANC-1, MIA PaCa-2, Capan-2, HPAF-II, Hs766T, A549, HEK293, and HEK293T cell lines were obtained from the Amer-ican Type Culture Collection (ATCC).
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br The lack of BIVA research in females limits
2020-08-18
The lack of BIVA research in females limits the ability to extrapolate results to women. Females differ physiologically to males (women generally have more body fat, less body water, shorter height and reduced muscle mass compared to men [41,42]). Of the three studies including women, two studied
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br expression was elevated by AC and TRAIL co treatment
2020-08-18
expression was elevated by AC and TRAIL co-treatment (Fig. 6). To-gether, these results indicate that AC-induced DR5 up-regulation is the initiating process of AC and TRAIL-induced synergistic apoptosis. 3.6. Co-treatment with AC and TRAIL suppresses phosphorylation of PI3K/ AKT/mTOR pathway
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br ACCEPTED MANUSCRIPT br Generalizability br The results of
2020-08-14
ACCEPTED MANUSCRIPT 4.4. Generalizability The results of this paper supported the results of previous studies as well as the rationale existing behind the tumor biology. All together show the external validity of our work. Although the significant association of KIR2DS5 did not remain signif
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br Keywords br Epithelial ovarian cancer br Human
2020-08-14
Keywords: Epithelial ovarian cancer Human chorionic gonadotrophin Luteinizing hormone Luteinizing hormone (LH)/hCG receptor Overall survival In addition to its critical role during pregnancy, human chorionic gonadotropin (hCG) has been shown to be expressed by various tumor types
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br In conclusion biomarkers of inflammation IL and CRP and
2020-08-14
In conclusion, biomarkers of Concanamycin A (IL-6 and CRP) and me-tabolism (resistin) were significantly associated with increased risk of cancer mortality independent of obesity, suggesting that both pathways may play a synergistic role in creating a favorable microenvironment for tumorigenesis
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br The protocol of the study was approved by
2020-08-14
The protocol of the study was approved by the Local Bioethics Committee (opinion no. KBET/98/B/2014). All procedures performed in this study involving human participants were in accordance with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. All the st
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br RNA extraction and qRT PCR experiment br
2020-08-12
RNA extraction and qRT-PCR experiment Total RNA was isolated from PCa and BPH tissues using Trizol reagent (Invitrogen) according to the manufacturer’s instructions. PrimeScript RT reagent Kit (Takara) was used for RNA transcription. The primers (Qing Ke Company) used in this study are presente
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br Published by Elsevier B
2020-08-12
© 2019 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/). 1. Introduction Lung cancer is the most common cause of malignant tumours world-wide [1].Of the different types of lung cancer, non-small cell
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br Introduction br Gallbladder cancer GBC a primary malignan
2020-08-12
1. Introduction Gallbladder cancer (GBC), a primary malignancy of the biliary tract, is the sixth most common gastrointestinal cancer and has a 5-year survival rate of 5% [1,2]. Although radical resection is the most pro-mising potential curative approach for patients, less than 10% of pa-tient
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br showed no significant change at to weeks P
2020-08-12
showed no significant change at to 5 weeks (P > 0.05); at 2 to 5 weeks, the average tumor inhibition rate of the Ad-VT treatment group was always higher than that of the other groups; the average tumor inhibition rate of the Ad-VT treatment group was significantly higher than that of the Ad-Mock t
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br D Daddiouaissa et al br the therapeutic
2020-08-12
D. Daddiouaissa, et al. the therapeutic effects of the fruit extract as well as the determination of the active compounds responsible for cytotoxicity. Conflicts of interest There is no conflict of interest in this work. Acknowledgment The authors are grateful to the International Is
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br Introduction br Alpha fetoprotein AFP is known as an
2020-08-12
1. Introduction Alpha-fetoprotein (AFP) is known as an embryonal serum glyco-protein that is normally synthesized from fetal hepatocytes and yolk sac UNC 1999 during the gestational period [1]. In adulthood, AFP is commonly regarded as a characteristic tumor biomarker for screening and super-vi